Oral Pain Relief Medications

Search the internet looking for effective remedies or painkillers for toothache pain. Several articles from major publications say that over-the-counter anti-inflammatory drugs such as ibuprofen, Advil, Motrin, or naproxen work best for dental pain because they reduce inflammation. However, if you ever have a toothache, you know they are full of shit! While these are especially useful because of their inflammation-reducing benefits, they fall short. More often than not, your best choice is over-the-counter pain relief. These come in liquid, gels, creams, and swabs form and can be used for temporary pain management. These products usually contain an active ingredient such as benzocaine that temporarily numbs the area until you can see a dentist. Take a look at 249 Smile’s selection of over-the-counter oral pain relief medications. These were voted the best by you, the consumers!

SaleBestseller No. 1

Orajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- From Oral Pain Relief Brand

INSTANT PAIN RELIEF: Instant pain relief with Orajel’s unique 4X clinical strength formula to help relieve pain of the tooth and gums
4X ACTIVE INGREDIENTS: With 4 active ingredients, Orajel Cream provides fast acting and maximum strength relief when you need it most
KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections

SaleBestseller No. 2

Orajel 3X for Toothache & Gum Pain: Maximum Gel Tube 0.42oz - From #1 Oral Pain Relief Brand - Orajel for Instant Pain Relief

INSTANT PAIN RELIEF: Instant pain relief with Orajel’s maximum strength formula to help relieve pain of the tooth and gums with 20% benzocaine
KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections
COOLING RELIEF: To help relieve gum irritation, Orajel toothache gel contains cooling relief

SaleBestseller No. 3

Anbesol Maximum Strength Oral Pain Relief Gel, Instant Pain Relief For Toothache Pain, Canker Sores, Sore Gums, Mouth Sores, Denture Pain, and Aligner Pain, ADA Accepted, 0.33 oz (packaging may vary)

INSTANT PAIN RELIEF: Instant oral pain relief for mouth and gum irritation due to toothaches, canker sores, sore gums, denture pain, and minor dental procedures. Use with dentures to relieve discomfort.
MAXIMUM STRENGTH: Instant relief that takes you from ouch to ahhh! So, oral pain doesn’t hold you back. Formulated with 20% Benzocaine to offer maximum strength pain relief and instantly soothe mouth pain and dental irritation
EASY TO USE: Cut the Tube Tip for easy access to the oral pain relief you need; Adults and children 2 years and over. Not for use in children under 2 years of age.

SaleBestseller No. 4

IODENT ORAL ANALGESIC GEL 0.42 OZ

Iodent Compare to the active ingredient of ORAJEL
ORAJEL

Bestseller No. 5

Orajel Maximum Strength Nighttime Toothache Pain Relief Cream - 0.25 Oz

B00433JHW2

Bestseller No. 6

Orajel 2X Medicated Toothache & Mouth Sores Liquid, 0.45 fl oz

20% Benzocaine to relieve oral pain
Menthol to soothe gums
Fast-acting liquid for instant pain relief

SaleBestseller No. 7

Orajel 3X for Mouth Sores: Maximum Strength Gel Tube 0.42oz- From #1 Oral Pain Relief Brand

INSTANT PAIN RELIEF: Orajel Mouth Sore Gel contains 20% Benzocaine to relieve pain from canker sores, mouth sores, cold sores and other mouth irritations
SOOTHING RELIEF: Maximum strength gel uses menthol to soothe irritated and sore gums quickly, where you need it most
PROTECTION: Our unique, fast acting, formula contains an astringent to help protect sores from irritation, including irritation from dentures or braces, as well as canker sores

SaleBestseller No. 8

Anbesol Maximum Strength Oral Pain Relief Gel, Instant Pain Relief for Toothache Pain, Canker Sores, Sore Gums, Mouth Sores, Denture Pain, and Aligner Pain, ADA Accepted, 0.33 oz (Packaging May Vary)

The information below is per-pack only
Instant Oral Pain Relief: Anbesol Maximum Strength gel for mouth pain, including toothache pain, canker sores, sore gums, mouth sores, denture pain, braces, retainer, and aligner pain, and minor dental procedures
OW to WOW! Instantly: Formulated with the active ingredient Benzocaine, an oral pain reliever, and numbs instantly to temporarily relieve toothaches, gum pain, canker sores and aligner pain

SaleBestseller No. 9

Anbesol Maximum Strength Oral Anesthetic Liquid - 0.41 fl oz (packaging may vary)

Instant Oral Pain Relief: Anbesol Maximum Strength Liquid for mouth pain, including toothache pain, canker sores, sore gums, mouth sores, denture pain, braces, retainer and aligner pain, and minor dental procedures
OW to WOW! Instantly: Formulated with the active ingredient Benzocaine, an oral pain reliever, and numbs instantly to temporarily relieve toothaches, gum pain, canker sores and aligner pain.
Liquid Formula: Anbesol Liquid Formula goes on clear and is undetectable, stays where you apply it, and provides fast and effective numbing of oral pain

SaleBestseller No. 10

Rite Aid Maximum Strength Liquid Anesthetic Oral Pain Relief - .5 fl oz, Benzocaine 20% | Pain Relief Medications & Treatments | Canker Sore and Tooth Pain Relief for Adults | Mouth Sores Treatment

MOUTH SORE TREATMENT: Rite Aid Max Strength Oral Liquid Anesthetic Benzocaine 20% pain relieving liquid temporarily relieves pain associated with toothaches, sore gums, mouth sores, canker sores, dentures/braces, cheek bites, and minor dental procedures.
FAST-ACTING PAIN RELIEF: Rite Aid offers instant relief from pain associated with toothaches, gum pain, canker sores, and dentures/braces. Compare Rite Aid to the leading national brand and get the same reliable mouth pain relief you can count on.
MAXIMUM STRENGTH: Formulated with 20% Benzocaine, Rite Aid Maximum Strength Liquid Anesthetic Oral Pain Relief offers the maximum amount of pain relief and aims to temporarily relief the mouth and tooth pain that ails you, so you can live pain free.

SaleBestseller No. 11

Benzodent Dental Pain Relieving Cream for Dentures and Braces, Topical Anesthetic, 0.25 Ounce Tube

FOR DENTAL PAIN: Benzodent provides temporary relief of pain for oral discomfort caused by dentures, braces or sores, with the maximum amount of benzocaine allowed in an over the counter oral product.
LONG LASTING RELIEF: Benzodent is a thick topical cream that provides pain relief with the strength of benzocaine. The unique formula cushions & adheres to gums for pain relief that lasts for hours.
GREAT FOR DENTURES OR BRACES: Dentures & braces can rub against your gums, tongue, or the inside of your cheeks and lips causing painful sores. Benzodent numbs the area for temporary pain relief.

Bestseller No. 12

DenTek Instant Oral Pain Relief Maximum Strength Kit for Toothaches | 50-Count per pack | 2-Pack

2-Pack. Each pack includes one bottle of Benzocaine (20%), 50-Count Disposable Applicators, Applicator Handle, and a Carrying Case.
Get instant relief from severe toothaches with Maximum Strength DenTek Instant Oral Pain Relief.
No fingers, No mess. Single-use disposable applicators. Dentist Recommended.

SaleBestseller No. 13

Canker-X Mouth Sore Spray, Oral Pain Relief from Canker Sores, Burns & More, No Burning & Numbing, Benzocaine-Free & Alcohol-Free Mouth Ulcer Treatment, Targeted Spray Nozzle, 0.51 Fl. Oz.

FAST PAIN RELIEF & HEALING MOUTH SORE SPRAY: Canker-X canker sore treatment spray provides fast, long-lasting pain relief from canker sores, abrasions and more, without any burning or numbing sensation. Clinically tested benzocaine-free & alcohol-free formula
MOUTH SORES TREATMENT: Canker-X soothes canker sores, cheek bites, mouth burns, abrasions from braces and dentures, and other types of mouth sores, relieving pain and promoting healing, while blocking irritants like food and drinks
SOOTHES, HYDRATES & PROTECTS: With the goodness of Aloe Vera, Sodium Hyaluronate, and Polyvinylpyrrolidone (PVP), this oral pain relief spray works by forming a micro-thin protective coating over mouth sores to quickly relieve pain and discomfort for up to 6 hours

Bestseller No. 14

Zilactin-B Fast Acting Canker Sore Treatment - Long Lasting Protection and Oral Pain Relief of Canker Sores, Mouth Sores and Gum Irritations, Made in USA, 0.25oz Gel, Pack of 1

Broad-Spectrum Formula: Provides immediate, long lasting oral pain relief of canker sores, mouth sores and gum irritation
Fast, Long-Lasting Relief: Contains a proprietary blend of ingredients including 10% Benzocaine for immediate, long lasting, oral pain relief
Bioadhesive Technology: Provides up to 6 hours of durable protection and relief so you can eat and drink pain free

SaleBestseller No. 15

Canker-X Mouth Sore Gel, Fast Pain Relief & Healing for Canker Sores, Cheek Bites and Oral Abrasions, Oral Pain Relief Gel, Benzocaine-Free and Alcohol-Free, Adults and Kids 6+ Years, 0.28 fl oz

FAST PAIN RELIEF & HEALING GEL: Canker-X canker sore treatment gel provides fast, long-lasting oral pain relief from canker sores, abrasions and more without any burning or numbing sensation. Clinically tested formula with NO Benzocaine and NO alcohol
MOUTH SORES TREATMENT: Canker-X soothes canker sores, cheek bites, mouth sores and mouth abrasions often caused by braces and dentures. The alcohol-free and benzocaine-free oral pain relief gel promotes healing and relieves pain
SOOTHES, HYDRATES & PROTECTS: The unique and clinically tested Canker-X gel formula contains Polyvinylpyrrolidone (PVP) which forms a micro-thin protective coating over a mouth sore to block irritants like food & drinks, and relieves discomfort for up to 6 hours

Bestseller No. 16

GeriCare Benzocaine 20% Maximum Strength Toothache & Oral Instant Pain Relief Gel 0.5 oz. Fast-Acting Numbing Pain Treatment for Toothaches, Gum Irritation, Sensitivity & Mouth Sores, (Pack of 1)

High-Potency Formula: With 20% Benzocaine, this gel stands out for its high concentration, delivering a powerful numbing effect to swiftly alleviate toothaches and oral pain. The 20% Benzocaine concentration ensures a rapid onset of relief, making it an excellent choice for those seeking quick and effective solutions to dental discomfort.
Rapid Onset: Experience instant relief as the gel's fast-acting formula quickly numbs the affected area, providing a comforting and soothing sensation. The precision applicator enables you to apply the gel exactly where it's needed, allowing for controlled and targeted relief. This feature enhances the user experience and ensures efficient utilization of the product.
Precision Applicator: The gel comes in a convenient 0.5oz tube equipped with a precision applicator, allowing for targeted application directly to the source of pain. This feature ensures maximum effectiveness and minimizes product waste. The compact size of the tube makes it a practical companion for individuals on the move. Whether you're traveling, at work, or simply out and about, you can conveniently carry this gel to address oral pain promptly.

Bestseller No. 17

Orajel Nonseptic Mouth Sore Rinse 16oz, Soothing Mint Flavor, Provides Pain Relief, Promotes Healing, 3-Pack

PAIN RELIEF: Orajel Mouthwash helps to provide you with temporary pain relief from your mouth sores and irritation.
PROMOTES HEALING: Specially formulated to help kill bacillus in your mouth and promote healing so you can feel better.
FOR ALL MOUTH SORES: From canker sores, to cheek bites, gum irritation, and sores from dentures or braces- Orajel Mouth Sore Rinse can help alleviate your pain from the comfort of your home.

Bestseller No. 18

Oral Pain Relief, 0.75 Gram Packets (Box of 144)

SaleBestseller No. 19

Rite Aid Severe Toothache and Gum Relief - 0.25 oz

MOUTH SORE TREATMENT: Rite Aid Severe Toothache & Gum Relief Benzocaine 20% pain relieving gel temporarily relieves pain associated with toothaches, sore gums, mouth sores, canker sores, dentures/braces, cheek bites, and minor dental procedures.
FAST-ACTING PAIN RELIEF: Rite Aid offers instant relief from pain associated with toothaches, gum pain, canker sores, and dentures/braces. Compare Rite Aid to the leading national brand and get the same reliable mouth pain relief you can count on.
FOR SEVERE PAIN: Formulated with 20% Benzocaine, Menthol 0.5%, and Zinc Chloride 0.15%, Rite Aid Rite Aid Severe Toothache & Gum Relief offers the maximum amount of pain relief and aims to temporarily relief the mouth and tooth pain that ails you.

Bestseller No. 20

Gengigel Hyaluronic Acid Oral Gel for Mouth & Gum Discomfort (20ml), Soothes Irritation, Promotes Natural Healing & Protects Delicate Oral Tissue, No Paraben or SLS, Vegan & Kosher

Targeted Relief from Oral Conditions: Gengigel Oral Gel helps alleviate pain caused by mouth ulcers, gum irritation, and minor wounds. Formulated with hyaluronic acid, it helps restore gum health and reduce discomfort around dental implants
Soothes, Heals & Protects: The gel soothes pain, forms a protective barrier over oral tissues, and promotes healing by speeding up recovery from minor issues, damaged or bleeding gums, food burns, and oral abrasions. Helps maintain good oral health
Suitable for Daily Use: Gengigel is vegan, kosher, and is a safe option for daily oral care, offering relief from gum problems, and irritation caused by braces, dentures, or aligners. Formulated without SLS, gluten, triclosan, parabens, and lactose

Choosing Oral Pain Relief Products

Oral pain can be a debilitating and distressing experience, affecting our capability to speak, eat and enjoy daily activities. Whether it is gum inflammation, toothache, or mouth sores, finding successful relief is vital for restoring comfort and oral health. Fortunately, many oral pain relief products are accessible on the market, ranging from over-the-counter medications to natural remedies. Anyway, picking the perfect product can be overwhelming, considering the wide range of options. In this essential guide, we will explore essential factors to consider when choosing oral pain relief products, empowering you to make informed decisions for the best oral care. Here is a complete guide on picking oral pain relief products:

Consider the pain type you are experiencing.

Different types of oral pain need different kinds of pain relief. For example, toothache pain is generally treated with over-the-counter pain relievers, such as acetaminophen or ibuprofen. Gum disease pain may need a prescription drug, such as antibiotics.

Think about your full health.

If you have any health situations, such as kidney or liver disease, you may need to reject certain pain relievers. Be sure to discuss with your doctor about which pain relievers are safe for you to take.

Read the reviews

There are many sites where you can read reviews of oral pain relief items. This can be a supportive way to get an idea of which products are most successful and have fewer bad effects.

Talk to your pharmacist or doctor

If you are still not sure about which oral pain relief product is best for you, discuss it with your pharmacist or doctor. They can help you pick a product that is effective and safe for you.

Consider the dosage

Over-the-counter pain relievers come in a range of dosages. Be sure to read the label perfectly and follow the instructions. If you are taking a prescription drug, be sure to take it as directed by your doctor.

Last update on 2025-05-26 at 21:31